Paris Saint-Germain vs Bayern Munich. Bayern, five-times winners, are back in the final for the first time since after ending a streak of four losses in the semi-final stage with Wednesday’s comfortable win over Lyon. PSG have reached the final for the first time, having struggled to translate their dominance of the French league into a real challenge in Europe until wins in Lisbon over Atalanta and RB Leipzig secured their place. For the first time since , the Champions League final will feature two teams who entered the competition as domestic champions, a throwback to the days of the old European Cup when only a country’s title winners were allowed to enter. Leipzig were unable to lay a glove on PSG, but while Bayern ended up winning by the same score-line against Lyon, the German club were far more reliant on their opponent’s wastefulness in front of goal. That is not something you would normally associate with Neymar but he has been squandering big chances since the competition moved to Portugal, against both Atalanta and Leipzig.
In so doing, he hoped to help suture the long-standing rift that the railroad had created between the city’s disparate halves. The building’s glazed, vaulted main concourse also evokes both the traditional iron-and-glass sheds of railroad terminals and the glass-roofed commercial galleries of northern Italian cities most notably, Milan’s Galleria Vittorio Emanuele II, although Turin boasts a couple of its own.
The tube-like station, which sits above the now-buried tracks, stretches more than 1, feet, the same length as the high-speed trains that stop here on their way to Paris and Rome. The station also serves regional and commuter rail lines and has a metro stop, as well as underground parking.
The Turin–Lyon high-speed railway is a rail line under construction between the cities of Turin Construction of the tunnel itself was initially planned to start in –, but the project was only approved in the mountains where the tunnel is bored, though the extensive reconnaissance tunneling has found none to date.
The Turin—Lyon high-speed railway is a rail line under construction between the cities of Turin and Lyon  . The core of the project is the Mont d’Ambin Base Tunnel , a It represents one third of the estimated overall cost of the project and is the only part of the line where work has started. Like the Swiss NRLA project, the line has twin aims of transferring freight traffic across the Alps from trucks to rail to reduce air pollution and CO2 emissions and of providing faster passenger transport to reduce air traffic.
The project has been criticized for its cost, because traffic both by motorway and by rail was decreasing when the project was decided,  for potential environmental risks during the construction of the tunnel,  and because airplanes will still, after including time to and from the airport and through security, be slightly faster over the full Milan – Paris route. Civil engineering work started in with the construction of access points and geological reconnaissance tunneling.
The worthiness of the new line was the subject of heated debate, primarily in Italy. After a attempt to start reconnaissance work near Susa Italy resulted in violent confrontations between opponents and police, an Italian governmental commission was set up in to study all the issues. An eighth summary paper focused on cost—benefit analysis was unveiled in June Since , the Turin—Modane railway connects Turin with Lyon via the
Turin–Lyon high-speed railway
It was held on the following dates:. Coins are contained in Festival Coin Packs. They are obtainable from the quests, a daily free Coin button once per day , through the Festival TLEs or from purchasing Festival bundles. Purchasing the Festival Pass with an in-app purchase grants additional rewards when a new tier is reached.
If the Improved Festival Pass is purchased, all Premium rewards in completed tiers will be awarded. Later bundles would give Pro Kit cards and credits as well.
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Elettromeccanica CM and Deuta-Werke will focus on train control systems, whilst Cattron-Theimeg Europe and Kiepe will be featuring remote radio-control equipment. EAO and Tecnel System will show pushbuttons and door sensors. Loco buffers feature in the range of General Meccanica Caprie, and Glova will show its onboard toilet systems.
Ford Torino Exterior
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speed skating Competition: Klubblöp Ösk ⋅ Men Sweden Rink: Eyravallen Örebro; Date: ; Records: Men, Samalog – Allround m/mDate: Men, m, Junior:Date: All, / , / , / , / , / , / , / , /
During five days, between 2 and 7 July , more than participants from 82 countries came to ESOF to learn about the last developments in all scientific disciplines. Indeed, ESOF was a fantastic way to make scientists, business executives, politicians, policy makers, journalists and the general public meet in one place. Scientists had the chance to meet personalities of the scientific world such as Julia Fischer primatologist or Anton Zeilinger quantum optics and nanophysics and Nobel Prize winners such as Peter Agre Chemistry, and Harold Kroto Chemistry, The Career Programme was very well developed with more than researchers present including PhDs, students and Post-docs.
This was both very entertaining and very instructive. For more entertainment, different events were organised such as a lunchtime reception, the famous ESOF party that took place in the Castello del Valentino in a stunning setting with dinner and music, a media party in the National Cinema Museum and the Youth Party. These gave the tempo to ESOF
Canada at the Olympic Winter Games
Right out the gate it is probably appropriate to remind everyone about our approach to Hot Wheels movie cars. Just like all the Retro Entertainment cars, we are more interested in the cars themselves than the movies they came from. At least when it comes to our approach here on the Lamley Blog. I am a movie geek Fargo remains my favorite movie , and love to see some of my favorite cars pop up on the big and small screen, but when it is time to showcase the mini versions of those cars, there are folks far more qualified to take the movie angle.
The Torino Scale is a method for categorizing the impact hazard associated with near-Earth “For an object with multiple potential collisions on a set of dates, a Torino Scale The comet C/ A1, which passed close to Mars in , was originally and would impact Earth at a relative speed of km/s (32, mph).
DOI: As HLSCs are easy to isolate and culture in vitro , there is a very good opportunity to test their therapeutic potential in several liver related diseases especially urea cycle disorders. The in vivo pro-regenerative effect of HLSCs and their secretome was first demonstrated in different models of acute liver injuries including acute liver injury induced by the analgesic drug N-acetyl-p-aminophen and fulminant hepatitis induced by D-galactosamine and lipopolysaccharide.
In addition, further research highlighted their effectivity in improving chronic liver diseases such as non-alcoholic steatohepatitis. This article aims to discuss some of the experimental and methodological aspects of our approach and highlights some of the broad spectrum therapeutic effects of HLSCs and their secretome in various different disease models. We will also focus on some of the different parameters that still remain challenging towards the use of HLSC-derived EVs as a tool for the delivery of functional proteins and mRNAs in urea cycle disorders.
The urea cycle is a process that primarily occurs in the liver and is involved in the elimination of toxic ammonia waste in the form of urea. It is a conglomerate of multiple enzymatic reactions involved in the endogenous production of arginine, ornithine, and citrulline, as well as the metabolism of adenosine monophosphate and removal of nitrogen waste. Some of these essential enzymes required to catalyse the urea cycle such as Argininosuccinate Synthase 1 ASS1 are also connected with the nitric oxide production pathway through the urea cycle .
Citrullinemia type I is a rare autosomal recessive genetic disorder caused by a deficiency of the enzyme ASS1. The role of ASS1 is to catalyse the condensation reaction between citrulline and aspartate to form argininosuccinic acid in the third step of the urea cycle . Mutations in the ASS1 gene results in the disruption of the urea cycle causing excessive accumulation of nitrogen.
A History Lesson At Torino’s MAuto
With a population of more than ,, Turin became the largest city ever to host the Olympic Winter Games. For the first time, live video coverage of the Games was available on mobile phones. Video coverage was available in 18 countries on five continents. In another first, television viewers in Mongolia and Azerbaijan were also able to watch all the action. Surfing the internet for results proved popular too, with torino Albania, Madagascar and Ethiopia were all represented for the first time.
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At times I feel a bit consumed by trying to keep up with the freshest and latest goings on in the car world. Then I check out the Speedhunters page to see what my colleagues elsewhere in the world have been working on overnight, before visiting various automotive news blogs in order to keep up to date with going ons. I had a few hours at my disposal in Torino last month before I had to jump back on the train and head home. While that is a great place and one I advise anyone in Japan to visit, what I really wanted to indulge in were some great Italian classics.
Take the engine here for example, a four cylinder unit with a massive 4, cc capacity which was only able to rev to a little over 1, rpm and develop all of 20hp. In contrast, the car that introduced mobility to Italy after the First World War was the Fiat , or Topolino as it was commonly known. This little car was powered by a tiny cc four-pot driving the rear wheels. In it replaced in with the Nuova — that little four-seater bubble car we all know and love. Looking at this Lancia Aprilia I felt pretty sad — sad because Fiat has allowed the Lancia brand to fade away into nothingness.
Back in the day Lancias were all about a combination of luxury, speed and looks, all mated to unusual engines. A capacity of just under 1. It was my first time seeing the Fiat Turbina in person. I remember hearing about this gas turbine powered experimental car years ago, but I never knew the finer details. Cisitalia is another of those marques that are long gone now.
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The Torino Scale is a method for categorizing the impact hazard associated with near-Earth objects NEOs such as asteroids and comets. It is intended as a communication tool for astronomers and the public to assess the seriousness of collision predictions, by combining probability statistics and known kinetic damage potentials into a single threat value. The Torino Scale uses an integer scale from 0 to A 0 indicates an object has a negligibly small chance of collision with the Earth , compared with the usual “background noise” of collision events, or is too small to penetrate Earth’s atmosphere intact.
A 10 indicates that a collision is certain, and the impacting object is large enough to precipitate a global disaster. An object is assigned a 0 to 10 value based on its collision probability and the kinetic energy expressed in megatons of TNT of the possible collision.
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In the Winter Games returned to Italy after a year absence. The competition venues were spread between seven villages most in the mountainous Piedmont region to the west and Turin, and beforehand there was some concern that the widespread Games would suffer from logistics problems and low attendance. The concerns proved to be unfounded, as the competitions were both exciting and well-attended.
International Olympic Committee IOC president Jacques Rogge , impressed with the large, happy crowds that the medal ceremonies routinely attracted, suggested that the concept be carried over to subsequent Olympiads. The Games were attended by approximately 2, athletes representing 80 countries. New events included speed skating team pursuit, mass-start biathlon races, and snowboard cross, which pits four boarders against each other in a thrilling race downhill through a series of jumps and sharp turns.
Michael Greis of Germany won three gold medals in biathlon events, but his success was overshadowed by the drug controversies in the Nordic skiing competition. Olga Pyleva , a Russian silver medalist in the biathlon, was disqualified after failing her drug test. Coach Walter Mayer , who had been banned for suspicion of blood doping , was discovered in the Austrian camp, which resulted in an investigation of 10 athletes.
The Russian team dominated the figure skating competition, collecting three gold medals and a bronze. Klassen won five medals in all—one gold, two silver, and two bronze. Ahn Hyun-Soo of South Korea dominated the short-track skating, winning three gold medals and one bronze. Turin Olympic Winter Games. Info Print Cite.
File:Torino Porta Susa 2014
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Affiliation DISAT and Center for Computational Sciences, Politecnico Torino, Torino, Italy along the three dimensions are as large as any reported to date. Received: February 28, ; Accepted: August 7, ; Published: more or less well from the data; a second motivation is computational speed.
Correlation patterns in multiple sequence alignments of homologous proteins can be exploited to infer information on the three-dimensional structure of their members. The typical pipeline to address this task, which we in this paper refer to as the three dimensions of contact prediction , is to i filter and align the raw sequence data representing the evolutionarily related proteins; ii choose a predictive model to describe a sequence alignment; iii infer the model parameters and interpret them in terms of structural properties, such as an accurate contact map.
We show here that all three dimensions are important for overall prediction success. In particular, we show that it is possible to improve significantly along the second dimension by going beyond the pair-wise Potts models from statistical physics, which have hitherto been the focus of the field. These simple extensions are motivated by multiple sequence alignments often containing long stretches of gaps which, as a data feature, would be rather untypical for independent samples drawn from a Potts model.
Using a large test set of proteins we show that the combined improvements along the three dimensions are as large as any reported to date. Proteins are large molecules that living cells make by stringing together building blocks called amino acids or peptides, following their blue-prints in the DNA. Freshly made proteins are typically long, structure-less chains of peptides, but shortly afterwards most of them fold into characteristic structures.
Proteins execute many functions in the cell, for which they need to have the right structure, which is therefore very important in determining what the proteins can do. The structure of a protein can be determined by X-ray diffraction and other experimental approaches which are all, to this day, somewhat labor-intensive and difficult. On the other hand, the order of the peptides in a protein can be read off from the DNA blue-print, and such protein sequences are today routinely produced in large numbers.
Signing up enhances your TCE experience with the ability to save items to your personal reading list, and access the interactive map. The idea of including winter sports in the Olympic Games dates back to , when organizers planned to include figure skating as part of the Games in Paris. Although it did not happen at the Games, figure skating exhibitions were held in October at the Olympic Games in London, won by Swedish skater Ulrich Salchow, originator of the jump that now bears his name.
one of the largest fast moving consumer goods (FMCG) companies globally. by this Annual Report and Accounts and up to the date of its approval by the Boards. KPMG have been the Group’s auditors since and shareholders approved their Italy – Piazza Paleocapa 1/D, , Torino. Gromart.
All information provided is deemed reliable but is not guaranteed and should be independently verified. Note: BeachHouse. Please contact the homeowner or agent directly by using this form. Tap or Swipe to see more photos. Save to Favorites. If you want luxury with an amazing kitchen, The Torino is perfect for you.